“魔鬼周”极限训练对武警特战队员生化指标的影响

 

目的 了解“魔鬼周”极限训练对武警特战队员身体状况的影响,以便更有效地预防和减少运动损伤,提高体能训练效果。方法 选取90例来自武警某部参加2017年第三季度“魔鬼周” 极限训练的特战队员作为研究对象,分别于“魔鬼周”的第1天及第7天进行肝功能、肾功能、血糖、血脂四项指标的检测,包括丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、总胆红素(T-Bil)、直接胆红素(D-Bil)、间接胆红素(IBIL)、尿素(UREA)、肌酐(CREA)、尿酸(UA)、血糖(Glu)、甘油三酯(TG)、胆固醇(TC)、高密度胆固醇(HDL-C)、低密度胆固醇(LDL-C)。应用SPSS 18.0统计软件进行数据处理。结果 训练后血清ALT、AST、UREA、CREA、UA、Glu、TG较训练前明显升高(P＜0.05),UREA、TC、LDL-C低于训练前(P＜0.05),T-Bil、D-Bil、IBIL、HDL-C训练前后无明显变化。结论 “魔鬼周”极限训练对武警特战队员的生理功能可产生一定的影响,进而可能影响其训练水平。

     

Preoperative nutritional status assessment predicts postoperative outcomes in patients with surgically resected non-small cell lung cancer

Background

As nutritional status plays an important role in outcomes after surgery, this study evaluated the association between preoperative nutritional status (NS) and postoperative outcomes after major resection for lung cancer.

Association between Dietary Inflammatory Index (DII) and Risk of Breast Cancer: a Case-Control Study

Background: Breast cancer (BrCa) is the most common cancer among women worldwide and is the secondleading cause of cancer-related death in women, in developed countries. This cancer is among the top five mostcommon cancers in Iran. Studies have shown that dietary components are implicated in the etiology of BrCa. Theexistence of molecular connections between inflammation and BrCa has been demonstrated via different bimolecularevents. Methods: We examined the ability of the dietary inflammatory index (DIITM) to predict the risk of BrCa.This included 145 cases and 148 controls, who attended the specialized centers. DII scores were computed basedon dietary intake assessed using a 168-item FFQ. Logistic regression models were used to estimate multivariableORs. Results: Modeling DII as a continuous variable in relation to risk of BrCa showed a positive association afteradjustment for age and energy (OR=1.76; 95% CI=1.43-2.18); and were nearly identical in the multivariable analyses(OR=1.80; 95% CI=1.42-2.28). DII as tertiles, and adjusting for age and energy, subjects in tertile 3 had an OR of 6.94(95% CI= 3.26-14.79; P-trend ≤0.0001) in comparison to subjects in tertile 1. After multivariable adjustment, resultswere essentially identical as in the model adjusting for age and energy (OR tertile 3vs1=7.24; 95% CI=3.14-16.68;P-trend ≤0.001). Sub group analyses revealed similar positive associations with HER 2 receptor +ve, progesteronereceptor +ve, estrogen receptor +ve and lymph node invasive cases. Conclusion: Subjects who consumed a morepro-inflammatory diet were at increased risk of BrCa compared to those who consumed a more anti-inflammatory diet.     

营养风险筛查工具(NRS-2002)对不可手术的食管鳞癌患者同步放化疗疗效和不良反应的相关性分析

目的 研究营养风险筛查工具(NRS-2002)对不可切除的局部晚期食管鳞癌(LAESCC)患者接受同步放化疗治疗的疗效及生存结果影响。 方法 回顾性分析2013-2015年浙江省人民医院放疗科行根治性同步放化疗治疗的LAESCC患者 105例,营养状况的筛查使用营养风险筛查工具NRS-2002量表,率间比较采用χ²检验,Kaplan-Meier法计算生存率,Logrank法检验,Cox回归模型预后因素分析。 结果 37.1%的患者在同步放化疗前就存在营养风险,NRS-2002评分≥3分的患者≥3级不良反应发生率显著高于评分为 1~2分者(P=0.007),所有患者的中位生存(OS)和无进展生存(PFS)分别为17.0个月和11.8个月,NRS-2002评分≥3分组的患者OS和PFS均显著低于评分为 1~2分者(均 P=0.000),进一步行多因素分析发现,评分≥3分是OS (P=0.000)和PFS (P=0.001)降低的独立预后因素。 结论 NRS-2002工具表明食管癌患者存在较高营养风险,而治疗前评分≥3分提示与不良反应增加及生存降低显著相关,值得进一步研究和应用。     

营养干预对食管癌同步放化疗疗效研究

目的 探讨营养干预治疗对食管癌同步放化疗患者疗效的影响。方法 前瞻性纳入2016-2017年安徽省肿瘤医院确诊为食管癌行放疗的患者46例,随机分为常规治疗组与营养干预组(各23例),观察两组患者放疗前后体重指数(BMI)、主观整体评估(PG-SGA)、血清白蛋白(ALB)、血红蛋白(HB)、白细胞(WBC)等客观营养指标的变化及放疗不良反应发生率。结果 放疗前两组年龄、性别、BMI、ALB、PLT、临床分期等具有可比性(P>0.05);营养干预组放疗后BMI较放疗前改善(21.52±2.67、21.13±2.73,P=0.000);干预组放疗后PG-SGA评分较放疗前明显降低(P=0.000);常规组放疗后BMI、HB、ALB、PLT、WBC水平较放疗前明显下降,且PG-SGA评分较放疗前更差(P<0.05);此外,干预组患者出现3级骨髓抑制发生率显著降低(4.34%∶8.68%,P=0.000)。结论 食管癌放疗患者存在较高的营养风险,营养干预治疗可改善患者营养状况,降低放疗不良反应发生率,有可能提高患者生活质量,改善生存预后。     

Tamil Nadu nutritional survey comparing children aged 0–3 years with the NCHS/CDC reference population

A cross-sectional nutritional survey of children belonging to Tamil Nadu State of India, aged 0–3 years was conducted on a representative sample of 2039 children. The collected data was analysed using the recommended indices of height-for-age and weight-for-height based on standard deviation (SD scores) and cross-classified using the SD scores. The nutritional status of these children was compared with the NCHS standard. Prevalence of stunting (27.6%), wasting (9.9%) and simultaneous wasting and stunting (10.7%) was high among the children studied: